α-Amylase/α-Glucosidase-IN-2

Names

[ CAS No. ]:
2446063-14-3

[ Name ]:
α-Amylase/α-Glucosidase-IN-2

Biological Activity

[Description]:

α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent α-amylase and α-glucosidase dual inhibitor with IC50 values of 13.02, 13.09 µM for α-amylase and α-glucosidase, respectively. α-Amylase/α-Glucosidase-IN-2 has the potential for the research of diabetic complications[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

IC50: 13.02 µM (α-amylase); 13.09 µM (α-glucosidase)[1].


[References]

[1]. Shamim S, et al. Synthesis and screening of (E)-3-(2-benzylidenehydrazinyl)-5,6-diphenyl-1,2,4-triazine analogs as novel dual inhibitors of α-amylase and α-glucosidase. Bioorg Chem. 2020 Aug;101:103979.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H16ClN5

[ Molecular Weight ]:
385.85

Related Compounds