DC-CPin711

Names

[ CAS No. ]:
2447559-21-7

[ Name ]:
DC-CPin711

Biological Activity

[Description]:

DC-CPin711 is a potent and selective inhibitor of CREB-binding protein (CBP) bromodomain with an IC50 of 0.0626 μM. DC-CPin711 arrests cell cycle at G1 phase and induces apoptosis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

[Target]

IC50: 0.0626 μM (CBP bromodomain)[1]


[References]

[1]. Chen Y, et al. Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain. Bioorg Chem. 2020 Aug;101:103991.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H22N4O2

[ Molecular Weight ]:
386.45

Related Compounds