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PAR-4 (1-6) amide (human) trifluoroacetate salt

Names

[ CAS No. ]:
245443-51-0

[ Name ]:
PAR-4 (1-6) amide (human) trifluoroacetate salt

[Synonym ]:
(2S)-2-[(2-{[{(2S)-1-[N-(2-Amino-1-hydroxyethylidene)-L-tyrosyl]-2-pyrrolidinyl}(hydroxy)methylene]amino}-1-hydroxyethylidene)amino]-N1-[(2S)-1-hydroxy-1-imino-3-methyl-2-butanyl]pentanediimidic aci d
Pentanediimidic acid, 2-[[2-[[[(2S)-1-[(2S)-2-[(2-amino-1-hydroxyethylidene)amino]-3-(4-hydroxyphenyl)-1-oxopropyl]-2-pyrrolidinyl]hydroxymethylene]amino]-1-hydroxyethylidene]amino]-N1-[(1S)-1-(hydr oxyiminomethyl)-2-methylpropyl]-, (2S)-

Biological Activity

[Description]:

PAR-4 (1-6) amide human is an N-terminal fragment of protease-activated receptor 4 (PAR4). PAR-4 (1-6) amide human induce platelet aggregation[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vitro]

PAR-4 (1-6) amide human (50, 100 µM) 诱导血小板聚集[1]。

[References]

[1]. Shimizu M, et al. Thrombin-induced platelet aggregation -effect of dabigatran using automated platelet aggregometry. Platelets. 2020;31(3):360-364.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
913.8±75.0 °C at 760 mmHg

[ Molecular Formula ]:
C28H42N8O8

[ Molecular Weight ]:
618.682

[ Flash Point ]:
506.5±37.1 °C

[ Exact Mass ]:
618.312561

[ LogP ]:
0.98

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.656

Related Compounds