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IL-2-IN-1

Names

[ CAS No. ]:
245747-10-8

[ Name ]:
IL-2-IN-1

Biological Activity

[Description]:

IL-2-IN-1 is a potent IL-2 inhibitor with an IC50 value of 1978 nM. IL-2-IN-1 shows antiproliferative activities[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology

[Target]

IL-2:1978 nM (IC50)


[In Vitro]

IL-2-IN-1 (compound 2) shows antiproliferative activities with IC50s of 340, 1266 nM for human PBMC and rat PBMC, respectively[1].

[References]

[1]. Djuric SW, et al. 3,5-Bis(trifluoromethyl)pyrazoles: a novel class of NFAT transcription factor regulator. J Med Chem. 2000 Aug 10;43(16):2975-81.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H12F6N4O2

[ Molecular Weight ]:
418.29


Related Compounds