1-Piperazineaceticacid, 4-methyl-, 2-[(5-nitro-2-furanyl)methylene]hydrazide
Names
[ CAS No. ]:
24632-47-1
[ Name ]:
1-Piperazineaceticacid, 4-methyl-, 2-[(5-nitro-2-furanyl)methylene]hydrazide
[Synonym ]:
Nifurpipone
UNII-G7274CK635
5-Nitro-2-furaldehyde 4-methylpiperazinoacethydrazone
5-Nitro-2-furaldehyde N'-methylpiperazinoacethydrazone
Nifurpiponum [INN-Latin]
Nifurpipone [INN]
5-Nitro-furfural-<(4-methyl-piperazino)-acetylhydrazon>
(4-methyl-piperazin-1-yl)-acetic acid (5-nitro-furan-2-ylmethylene)-hydrazide
Nifurpipona [INN-Spanish]
Rec 15 0122
Chemical & Physical Properties
[ Density]:
1.41g/cm3
[ Molecular Formula ]:
C12H17N5O4
[ Molecular Weight ]:
295.29400
[ Exact Mass ]:
295.12800
[ PSA ]:
106.90000
[ LogP ]:
0.67520
[ Index of Refraction ]:
1.635
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TK7906700
- CHEMICAL NAME :
- 1-Piperazineacetic acid, 4-methyl-, (5-nitrofurfurylidene)hydrazide
- CAS REGISTRY NUMBER :
- 24632-47-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C12-H17-N5-O4
- MOLECULAR WEIGHT :
- 295.34
- WISWESSER LINE NOTATION :
- T6N DNTJ A1 D1VMNU1- BT5OJ ENW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 990 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,73,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 212 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,73,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 880 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 114,73,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 315 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 14,633,1971
Safety Information
[ HS Code ]:
2934999090
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%