Thiamine pyrophosphate-d3

Names

[ Name ]:
Thiamine pyrophosphate-d3

Biological Activity

[Description]:

Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₆D₃ClN₄O₇P₂S

[ Molecular Weight ]:
463.79

Thiamine pyrophosphate-d3

Names

Biological Activity

Chemical & Physical Properties

Related Compounds