α-Synuclein inhibitor 4

Names

[ CAS No. ]:
2489813-08-1

[ Name ]:
α-Synuclein inhibitor 4

Biological Activity

[Description]:

α-Synuclein inhibitor 4 (compound 3gh) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 0.98 μM and inhibition ratio at 30 μM of 91.2%[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[Target]

IC50: 0.98 ± 0.58 μM (α-Synuclein)[1]


[References]

[1]. Chen L, et al. Amide derivatives of Gallic acid: Design, synthesis and evaluation of inhibitory activities against in vitro α-synuclein aggregation. Bioorg Med Chem. 2020 Aug 1;28(15):115596.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H16N2O6

[ Molecular Weight ]:
380.35

Related Compounds