MRGPRX4 modulator-2

Names

[ Name ]:
MRGPRX4 modulator-2

Biological Activity

[Description]:

MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

IC50: < 100 nM (MRGPR X4)[1]

[References]

[1]. Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 (compound 1-55)

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₉ClF₄O₃

[ Molecular Weight ]:
348.68

MRGPRX4 modulator-2

Names

Biological Activity

Chemical & Physical Properties

Related Compounds