Antiparasitic agent-5

Names

[ CAS No. ]:
2494276-55-8

[ Name ]:
Antiparasitic agent-5

Biological Activity

[Description]:

Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC50 = 6.78 μM)[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

IC50: 2.50 μM (L. infantum)[1]


[References]

[1]. Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H16ClN3O3

[ Molecular Weight ]:
381.81

Related Compounds