ANO1-IN-3

Names

[ CAS No. ]:
2494280-04-3

[ Name ]:
ANO1-IN-3

Biological Activity

[Description]:

ANO1-IN-3 (Compound 3n) is a potent and selective ANO1 inhibitor with an IC50 of 1.23 μM. ANO1-IN-3 induces apoptosis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Signaling Pathways >> Membrane Transporter/Ion Channel >> Chloride Channel

[Target]

IC50: 1.23 μM (ANO1)[1]

[References]

[1]. Seo Y, et al. Diversity-oriented generation and biological evaluation of new chemical scaffolds bearing a 2,2-dimethyl-2H-chromene unit: Discovery of novel potent ANO1 inhibitors. Bioorg Chem. 2020 Aug;101:104000.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₇NO₃

[ Molecular Weight ]:
319.35

Related Compounds