MALT1-IN-3

Names

[ CAS No. ]:
2504229-63-2

[ Name ]:
MALT1-IN-3

Biological Activity

[Description]:

MALT1-IN-3 (compound 122) is a potent MALT1 protease inhibitor, with an IC50 of 0.06 μM. MALT1-IN-3 has IC50 of 0.14 and 0.13 μM for human IL6/IL10 in OCI-LY3 cells, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> NF-κB >> MALT1

[Target]

IC50: 0.06 μM (MALT1)[1]


[References]

[1]. Johannes Wilhelmus J Thuring, et al. Pyridine rings containing derivatives as malt1 inhibitors. WO2020208222A1

Chemical & Physical Properties

[ Molecular Formula ]:
C21H19F3N8O2

[ Molecular Weight ]:
472.42

Related Compounds