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BB 0305179

Names

[ CAS No. ]:
2512200-83-6

[ Name ]:
BB 0305179

Biological Activity

[Description]:

BB 0305179 (compound 59) is a potent anti-prion agent, with an IC50 of 4.7 μM. BB 0305179 inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain [1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[Target]

IC50: 4.7 ± 1.9 μM (PrPSc)[1]


[References]

[1]. Altieri A, et al. Generation, optimization and characterization of novel anti-prion compounds. Bioorg Med Chem. 2020 Nov 1;28(21):115717.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H29NO

[ Molecular Weight ]:
311.46

Related Compounds