Cholecystokinin Octapeptide (sulfated) ammonium salt

Names

[ Name ]:
Cholecystokinin Octapeptide (sulfated) ammonium salt

[Synonym ]:
(3S,6S,9S,15S,18S,21S)-21-amino-3-{[(1S)-2-amino-1-benzyl-2-oxoethyl]carbamoyl}-9-(1H-indol-3-ylmethyl)-6,15-bis[2-(methylsulfanyl)ethyl]-5,8,11,14,17,20-hexaoxo-18-[4-(sulfooxy)benzyl]-4,7,10,13,16,19-hexaazatricosane-1,23-dioic acid
Sincalide
L-Phenylalaninamide, L-α-aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-
CCK 26-33,SULFATED
L-a-Aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-a-aspartyl-L-phenylalaninamide
Sincalide Acetate
MFCD00079849
CCK OCTAPEPTIDE SULFATED
CCK-8 Cholecystokinin octapeptide Pancreozymin C-terminal octapeptide Sincalide
L-α-Aspartyl-O-sulfo-L-tyrosyl-L-methionylglycyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide
CCKC-Terminal Octapeptide
cck-8
cholecystokinin octapeptide
cholecystokinin-26-33
Cholecystokinin C-terminal Octapeptide
Pancreozymin C-terminal octapeptide

Biological Activity

[Description]:

Sincalide is a rapid-acting, synthetic analog of cholecystokinin for intravenous use in postevacuation cholecystography. Sequence: Asp-{SO3H-Tyr}-Met-Gly-Trp-Met-Asp-Phe-NH2.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Cancer

Peptides

[References]

[1]. Maher KA et al. Kinevac (sincalide for injection)/Squibb Diagnostics. Gastroenterol Nurs. 1991 Oct;14(2):98-100.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₄₉H₆₂N₁₀O₁₆S₃

[ Molecular Weight ]:
1143.269

[ Exact Mass ]:
1142.350708

[ PSA ]:
485.78000

[ LogP ]:
2.25

[ Index of Refraction ]:
1.643

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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