α-Hydroxymethyl Atropine
Names
[ CAS No. ]:
2515-36-8
[ Name ]:
α-Hydroxymethyl Atropine
[Synonym ]:
(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-(hydroxymethyl)-2-phenylpropanoate
Chemical & Physical Properties
[ Density]:
1.24g/cm3
[ Boiling Point ]:
489.2ºC at 760 mmHg
[ Molecular Formula ]:
C18H25NO4
[ Molecular Weight ]:
319.39500
[ Flash Point ]:
249.7ºC
[ Exact Mass ]:
319.17800
[ PSA ]:
70.00000
[ LogP ]:
1.01530
[ Vapour Pressure ]:
2.2E-10mmHg at 25°C
[ Index of Refraction ]:
1.595
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CY1575200
- CHEMICAL NAME :
- Benzeneacetic acid, alpha,alpha-bis(hydroxymethyl)-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-(+-)-
- CAS REGISTRY NUMBER :
- 2515-36-8
- BEILSTEIN REFERENCE NO. :
- 1549723
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H25-N-O4
- MOLECULAR WEIGHT :
- 319.44
- WISWESSER LINE NOTATION :
- T56 A ANTJ A1 FOVXR&O1&O1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 43 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 35,59,1972