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2’-Deoxy-2’-fluoro-b-D-arabinocytidine hydrochloride

Names

[ CAS No. ]:
25183-22-6

[ Name ]:
2’-Deoxy-2’-fluoro-b-D-arabinocytidine hydrochloride

Biological Activity

[Description]:

2’-Deoxy-2’-fluoro-b-D-arabinocytidine(hydrochloride) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds