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Pregn-4-ene-3,11,20-trione,9-bromo- (6CI,7CI,8CI,9CI)

Names

[ CAS No. ]:
2527-11-9

[ Name ]:
Pregn-4-ene-3,11,20-trione,9-bromo- (6CI,7CI,8CI,9CI)

[Synonym ]:
9-Bromopregn-4-ene-3,11,20-trione
9-Brom-pregn-4-en-3,11,20-trion
Braxorone

Chemical & Physical Properties

[ Density]:
1.36g/cm3

[ Boiling Point ]:
517.3ºC at 760mmHg

[ Molecular Formula ]:
C21H27BrO3

[ Molecular Weight ]:
407.34100

[ Flash Point ]:
102.4ºC

[ Exact Mass ]:
406.11400

[ PSA ]:
51.21000

[ LogP ]:
4.42000

[ Vapour Pressure ]:
8.32E-11mmHg at 25°C

[ Index of Refraction ]:
1.575

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU5514000
CHEMICAL NAME :
Pregn-4-ene-3,11,20-trione, 9-bromo-
CAS REGISTRY NUMBER :
2527-11-9
LAST UPDATED :
198910
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C21-H27-Br-O3
MOLECULAR WEIGHT :
407.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
13 mg/kg
SEX/DURATION :
female 21 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 76,626,1958
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
18 mg/kg
SEX/DURATION :
female 15 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
OBGNAS Obstetrics and Gynecology. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1953- Volume(issue)/page/year: 10,411,1957
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
DOSE :
200 ug/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 71,494,1958

Related Compounds