CYP3A4 enzyme-IN-1

Names

[ CAS No. ]:
2531281-25-9

[ Name ]:
CYP3A4 enzyme-IN-1

Biological Activity

[Description]:

CYP3A4 enzyme-IN-1 (compound 59) is a potent antibacterial agent, with a MIC of 1 μg/mL for MRSA. CYP3A4 enzyme-IN-1 exhibits low to moderate inhibitory effects on CYP1A2, CYP2E1, CYP2D6, and CYP3A4 enzymes[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Zhang GY, et, al. Design, synthesis and biological evaluation of novel pleuromutilin derivatives containing piperazine and 1,2,3-triazole linker. Bioorg Chem. 2020 Dec;105:104398.

Chemical & Physical Properties

[ Molecular Formula ]:
C41H58N8O7

[ Molecular Weight ]:
774.95

Related Compounds