4'-Hydroxy diclofenac D4
Names
[ CAS No. ]:
254762-27-1
[ Name ]:
4'-Hydroxy diclofenac D4
Biological Activity
[Description]:
4'-Hydroxy diclofenac D4 is the deuterium labeled 4'-Hydroxy diclofenac. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[1][2].
[Related Catalog]:
[In Vitro]
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[References]
Chemical & Physical Properties
[ Density]:
1.54g/cm3
[ Boiling Point ]:
432.709ºC at 760 mmHg
[ Molecular Formula ]:
C14H7Cl2D4NO3
[ Molecular Weight ]:
316.17300
[ Flash Point ]:
215.495ºC
[ Exact Mass ]:
315.03700
[ PSA ]:
69.56000
[ LogP ]:
4.14270
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.69
[ Storage condition ]:
-20°C