7-Methoxy-4-methylcoumarin

Names

[ Name ]:
7-Methoxy-4-methylcoumarin

[Synonym ]:
METHYL-7-METHOXYCOUMARIN,4
Herniarin,4-methyl
4-methyl-7-methyloxycoumarin
4-METHYL-7-METHOXYCOUMARIN
7-Methoxy-4-methylcoumarin
Coumarin,7-methoxy-4-methyl
Methyl 4-methylumbelliferyl ether
T66 BOVJ E1 IO1
4-methyl-7-methoxy-2H-1-benzopyran-2-one
7-Methoxy-4-methyl-2H-chromen-2-on
7-Methoxy-4-methylchromen-2-one
7-Methoxy-4-Methylcourmain
7-Methoxy-4-methyl-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 7-methoxy-4-methyl-
4-Methylherniarin
7-Methoxy-4-Methylcoumarine
7-methoxy-4-methyl-chromen-2-one
7-Methoxy-4-methyl-2H-chromen-2-one
MFCD00009773
Hymechrome methyl ether

Biological Activity

[Description]:

4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 values of 11.76 μg/ml and 13.47 μg/ml[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

IC50: 11.76 μg/ml (B. subtilis); 13.47 μg/ml (S.sonnei)[1]

[References]

[1]. Fauzia Anjum Chattha, et al. Potential antibacterial activity of coumarin and coumarin-3-acetic acid derivatives

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
340.1±37.0 °C at 760 mmHg

[ Melting Point ]:
158-160 °C(lit.)

[ Molecular Formula ]:
C₁₁H₁₀O₃

[ Molecular Weight ]:
190.195

[ Flash Point ]:
140.8±21.1 °C

[ Exact Mass ]:
190.062988

[ PSA ]:
39.44000

[ LogP ]:
2.37

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.556

[ Stability ]:
Moisture, Temperature Sensitive

[ Water Solubility ]:
DMF: soluble

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%