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BTK inhibitor 19

Names

[ CAS No. ]:
2557174-19-1

[ Name ]:
BTK inhibitor 19

Biological Activity

[Description]:

BTK inhibitor 19 is a highly selective, covalent BTK inhibitor (IC50 = 2.7 nM).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

[References]

[1]. Ma C, et al. Discovery of 1-Amino-1H-imidazole-5-carboxamide Derivatives as Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitors. J Med Chem. 2021 Nov 11;64(21):16242-16270.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₄F₃N₇O₃

[ Molecular Weight ]:
527.50

Related Compounds