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(S,S)-J-113397

Names

[ CAS No. ]:
256640-46-7

[ Name ]:
(S,S)-J-113397

Biological Activity

[Description]:

(S,S)-J-113397 is an isomer of J-113397 (HY-114072). J-113397 is an Opioid Receptor antagonist[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor
Signaling Pathways >> Neuronal Signaling >> Opioid Receptor
Research Areas >> Neurological Disease

[References]

[1]. Kawamoto H, et al. Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3 R, 4 R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2 H-benzimidazol-2-one (J-113397)[J]. Journal of medicinal chemistry, 1999, 42(25): 5061-5063.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H37N3O2

[ Molecular Weight ]:
399.57

Related Compounds