2-Methylbutyrylcarnitine

Names

[ Name ]:
2-Methylbutyrylcarnitine

[Synonym ]:
1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-(2-methyl-1-oxobutoxy)-, inner salt, (2R)-
(3R)-3-[(2-Methylbutanoyl)oxy]-4-(trimethylammonio)butanoate
2-methylbutyryl-L-carnitine
(R)-2-methylbutyrylcarnitine
(2R)-3-Carboxy-N,N,N-trimethyl-2-(2-methyl-1-oxobutoxy)-1-propanaminium inner salt
MFCD11975299
2-methyl butyroyl carnitine
2-methylbutyrylcarnitine
5946881

Biological Activity

[Description]:

2-Methylbutyrylcarnitine is a fatty acid metabolite. 2-Methylbutyrylcarnitine is found mainly in the blood and urine of humans and animals and is produced through the pyruvate carboxylation pathway. 2-Methylbutyrylcarnitine exhibits high level in the plasma of subjects with steatohepatitis (NASH) and can be used as an indicator for the diagnosis of metabolic diseases[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Kalhan SC, et al. Plasma metabolomic profile in nonalcoholic fatty liver disease. Metabolism. 2011 Mar;60(3):404-13.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₂₃NO₄

[ Molecular Weight ]:
245.32

[ Exact Mass ]:
245.162704

[ LogP ]:
-2.74

[ Storage condition ]:
2-8°C