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eIF4E-IN-1

Names

[ CAS No. ]:
2573979-31-2

[ Name ]:
eIF4E-IN-1

Biological Activity

[Description]:

eIF4E-IN-1 is a potent inhibitor of eIF4E. eIF4E-IN-1 inhibits immunosuppression components such as immune checkpoint proteins PD-1, PD-L1, LAG3, TIM3, and/or IDO, in order to inhibit or release immune suppression in certain diseases, such as cancer and infectious disease (extracted from patent WO2021003194A1, compound Y)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Eukaryotic Initiation Factor (eIF)
Research Areas >> Infection

[Target]

eIF4E[1]


[References]

[1]. Kevin R, et al. Eif4e inhibitors for use as immune checkpoint modulators and related methods. Patent WO2021003194A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H28ClF3N6O4S

[ Molecular Weight ]:
697.13

Related Compounds