2-[3-(4-chlorobenzoyl)-6-methoxy-2-methylindol-1-yl]acetic acid

Names

[ CAS No. ]:
25803-14-9

[ Name ]:
2-[3-(4-chlorobenzoyl)-6-methoxy-2-methylindol-1-yl]acetic acid

[Synonym ]:
6-Methoxy-2-methyl-3-p-chlorbenzoylindol-1-yl-essigsaeure
Clometacina [INN-Spanish]
Clomethacin
Clometazin
Clometacine [INN-French]
Clometacin
Clometacine
3-p-Chlorbenzoyl-2-methyl-6-methoxyindol-1-yl-essigsaeure
EINECS 247-271-3
Clometacinum [INN-Latin]
Clometacin [INN:DCF]
Duperan
[3-(4-chloro-benzoyl)-6-methoxy-2-methyl-indol-1-yl]-acetic acid

Chemical & Physical Properties

[ Density]:
1.32g/cm3

[ Boiling Point ]:
564ºC at 760 mmHg

[ Molecular Formula ]:
C19H16ClNO4

[ Molecular Weight ]:
357.78800

[ Flash Point ]:
294.9ºC

[ Exact Mass ]:
357.07700

[ PSA ]:
68.53000

[ LogP ]:
3.92730

[ Vapour Pressure ]:
1.47E-13mmHg at 25°C

[ Index of Refraction ]:
1.619

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL3490000
CHEMICAL NAME :
Indole-1-acetic acid, 3-(p-chlorobenzoyl)-6-methoxy-2-methyl-
CAS REGISTRY NUMBER :
25803-14-9
BEILSTEIN REFERENCE NO. :
1552200
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C19-H16-Cl-N-O4
MOLECULAR WEIGHT :
357.81
WISWESSER LINE NOTATION :
T56 BNJ B1VQ C1 DVR DG& HO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 10,187,1975

Safety Information

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds