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p38α inhibitor 3

Names

[ CAS No. ]:
260428-69-1

[ Name ]:
p38α inhibitor 3

[Synonym ]:
(4-Benzyl-piperidin-1-yl)-(4-fluoro-phenyl)-methanone
Methanone, (4-fluorophenyl)[4-(phenylmethyl)-1-piperidinyl]-
(4-Benzyl-1-piperidinyl)(4-fluorophenyl)methanone

Biological Activity

[Description]:

p38α inhibitor 3 (Comp G7) is a p38α inhibitor that blocks the effectiveness of myoblast differentiation[1].

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK
Research Areas >> Inflammation/Immunology

[References]

[1]. Yael Friedmann, et al. JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast. Mol Pharmacol. 2006 Oct;70(4):1395-405.   

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
443.9±28.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H20FNO

[ Molecular Weight ]:
297.3666032

[ Flash Point ]:
222.3±24.0 °C

[ Exact Mass ]:
297.152893

[ LogP ]:
3.65

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.579

Related Compounds