N-Methyl(2H)formamide

Names

[ Name ]:
N-Methyl(2H)formamide

[Synonym ]:
N-Methyl(H)formamide
N-methylformamide-1-d
C-deuterio-N-methyl-formamide
cadmium bromide * 2 triphenyl phosphine
Formamide-d, N-methyl-
Cadmiumbromid * 2 Triphenylphosphin

Biological Activity

[Description]:

N-Methylformamide-d1 is the deuterium labeled N-Methylformamide[1].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
182.5±9.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂H₄DNO

[ Molecular Weight ]:
60.073

[ Flash Point ]:
81.5±3.7 °C

[ Exact Mass ]:
60.043392

[ PSA ]:
29.10000

[ LogP ]:
-0.60

[ Vapour Pressure ]:
0.8±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.364

N-Methyl(2H)formamide

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds