4H-1,13-Methano[1,7]dioxacyclotridecino[4,3-b]pyrrole-6,11-dione,10-ethylidene-2,7,8,9,10,13,14,14a-octahydro-7,14-dihydroxy-7,8-dimethyl-,(7R,8R,10E,13S,14R,14aR)- (9CI)

Names

[ Name ]:
4H-1,13-Methano[1,7]dioxacyclotridecino[4,3-b]pyrrole-6,11-dione,10-ethylidene-2,7,8,9,10,13,14,14a-octahydro-7,14-dihydroxy-7,8-dimethyl-,(7R,8R,10E,13S,14R,14aR)- (9CI)

[Synonym ]:
(15E)-12,18-dihydroxy-senecionane-11,16-dione
Senecionan-11,16-dione,12,18-dihydroxy-,(15E)
trans-Retrorsine
(+)-Usaramine
Mucronatine
madurensine
trans-Retrorsin
Mucronatine (7CI)
Usaramin
C18H25NO6
(15E)-Retrorsine
(+)-Ursamine

Chemical & Physical Properties

[ Density]:
1.325g/cm3

[ Boiling Point ]:
612.375ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₅NO₆

[ Molecular Weight ]:
351.39400

[ Flash Point ]:
324.153ºC

[ Exact Mass ]:
351.16800

[ PSA ]:
96.30000

[ LogP ]:
0.10150

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.588

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OM0850000

CHEMICAL NAME :: Madurensine

CAS REGISTRY NUMBER :: 26126-78-3

LAST UPDATED :: 199012

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C18-H25-N-O6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Liver - other changes

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 12,299,1976