c[Arg-Arg-Arg-Arg-Dip-Dip-Dip]

Names

[ CAS No. ]:
2619853-87-9

[ Name ]:
c[Arg-Arg-Arg-Arg-Dip-Dip-Dip]

Biological Activity

[Description]:

c[Arg-Arg-Arg-Arg-Dip-Dip-Dip] (Compound 8C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 12.5 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Sandeep Lohan, et al. Small Amphiphilic Peptides: Activity Against a Broad Range of Drug-Resistant Bacteria and Structural Insight into Membranolytic Properties. J Med Chem. 2022 Jan 13;65(1):665-687.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₉H₈₇N₁₉O₇

[ Molecular Weight ]:
1294.55

c[Arg-Arg-Arg-Arg-Dip-Dip-Dip]

Names

Biological Activity

Chemical & Physical Properties

Related Compounds