<Suppliers Price>

Escin IB

Names

[ CAS No. ]:
26339-90-2

[ Name ]:
Escin IB

[Synonym ]:
2-butenoic acid, 2-methyl-, (3β,16α,21β,22α)-22-(acetyloxy)-3-[[O-β-D-glucopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranuronosyl]oxy]-16,24,28-trihydroxyolean-12-en-21-yl ester, (2Z)-
(3β,16α,21β,22α)-22-Acetoxy-16,24,28-trihydroxy-21-{[(2Z)-2-methyl-2-butenoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1-&gt;4)]-β-D-glucopyranosiduronic &#xA; acid
Escin Ib
Aescin
(3β,16α,21β,22α)-22-Acetoxy-16,24,28-trihydroxy-21-{[(2Z)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1-&gt;4)]-β-D-glucopyranosiduronic acid
Escin-IB
2-Butenoic acid, 2-methyl-, (3β,16α,21β,22α)-22-(acetyloxy)-3-[[O-β-D-glucopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranuronosyl]oxy]-16,24,28-trihydroxyolean-12 &#xA;-en-21-yl ester, (2Z)-
Aescin B
EINECS 247-619-4

Biological Activity

[Description]:

Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[Target]

Pancreatic lipase[2]


[References]

[1]. Abudayeh ZH, et al. Determination of Four Major Saponins in Skin and Endosperm of Seeds of Horse Chestnut (Aesculus Hippocastanum L.) Using High Performance Liquid Chromatography with Positive Confirmation by Thin Layer Chromatography. Adv Pharm Bull. 2015 Nov;5(4):587-91.

[2]. Hu JN, et al. Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata BLUME (Hippocastanaceae). Chem Pharm Bull (Tokyo). 2008 Jan;56(1):12-6.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
1140.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C55H86O24

[ Molecular Weight ]:
1131.257

[ Flash Point ]:
311.8±27.8 °C

[ Exact Mass ]:
1130.550903

[ PSA ]:
388.04000

[ LogP ]:
1.88

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.628

Related Compounds