p53 Activator 3

Names

[ CAS No. ]:
2636839-90-0

[ Name ]:
p53 Activator 3

Biological Activity

[Description]:

p53 Activator 3 (compound 87A) is a potent p53 activator with a SC150 value of <0.05 mM. p53 Activator 3 can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA. p53 Activator 3 shows anti-tumor activity[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Apoptosis >> MDM-2/p53

[References]

[1]. VU, Binh, et al. Methods and compounds for restoring mutant p53 function, WO2021061643.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H37F3N4O4S

[ Molecular Weight ]:
606.70

Related Compounds