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Lp-PLA2-IN-6

Names

[ CAS No. ]:
2637485-13-1

[ Name ]:
Lp-PLA2-IN-6

Biological Activity

[Description]:

Lp-PLA2-IN-6 (compound 18), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.0 for rhLp-PLA2. Lp-PLA2-IN-6 has the potential for neurodegenerative related diseases research[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase
Research Areas >> Neurological Disease

[References]

[1]. Qiong Xiao, et al. Tetracyclic pyrimidinone compounds, preparation method, composition and application thereof. CN112574221B.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H21F5N4O3

[ Molecular Weight ]:
520.45

Related Compounds