H-Arg-Arg-AMC hydrochloride salt

Names

[ Name ]:
H-Arg-Arg-AMC hydrochloride salt

[Synonym ]:
RR-MCA
Arg-Arg-MCA
H-ARG-ARG-AMC . 3HCL
H-ARG-ARG-AMC

Biological Activity

[Description]:

Arg-Arg-AMC is a highly selective substrate of Cathepsin B. Arg-Arg-AMC can be used to cathepsin B activity assay in cancer cells, while cathepsin B is assocaited with cell invasive and metastatic phenotype in numerous types of cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin

[Target]

Cathepsin B[1]

[References]

[1]. Hulkower KI, et al. Fluorescent microplate assay for cancer cell-associated cathepsin B. Eur J Biochem. 2000 Jul;267(13):4165-70.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₃N₉O₄

[ Molecular Weight ]:
487.56

[ Exact Mass ]:
487.26600

[ PSA ]:
238.23000

[ LogP ]:
2.92460

H-Arg-Arg-AMC hydrochloride salt

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds