CDK7-IN-7

Names

[ Name ]:
CDK7-IN-7

[Description]:

CDK7-IN-7 is a potent and selective CDK7 kinase inhibitor with an IC50 of <50 nM (Patent CN112661745A, compound T-01)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[Target]

CDK7:<50 nM (IC50)

[In Vitro]

CDK7-IN-7 shows inhibitory against MDA‑MB 231, MDA-MB453, OVCAR3, A2780, HCT-116, WiDr and Calu-6 cells (IC50 ranging from 12.21 to 144.9 nM)[1].

[References]

[ Molecular Formula ]:
C₂₀H₂₀BrF₃N₆O₂

[ Molecular Weight ]:
513.31