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Mal-VC-PAB-PNP-CDN-A

Names

[ CAS No. ]:
2640880-35-7

[ Name ]:
Mal-VC-PAB-PNP-CDN-A

Biological Activity

[Description]:

Mal-VC-PAB-PNP-CDN-A is a drug-linker conjugate for ADC[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

[References]

[1]. Chen, Zhijian, et al. ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY. Patent. US20210015941A1.

[2]. Wang Y, et al. Development of applicable thiol-linked antibody-drug conjugates with improved stability and therapeutic index. Drug Deliv. 2022 Dec;29(1):754-766.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₁H₆₇N₁₇O₂₀P₂

[ Molecular Weight ]:
1300.13

Related Compounds