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DHPS-IN-1

Names

[ CAS No. ]:
2643300-54-1

[ Name ]:
DHPS-IN-1

Biological Activity

[Description]:

DHPS-IN-1, with the best DHPS inhibitory potency (IC50 = 0.014 μM), exhibits excellent inhibition against melanoma cells.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Liu KL, et al. Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation. J Med Chem. 2021 Sep 23;64(18):13356-13372.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H13BrClN3O2

[ Molecular Weight ]:
406.66

Related Compounds