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B-Raf IN 2

Names

[ CAS No. ]:
2649372-20-1

[ Name ]:
B-Raf IN 2

Biological Activity

[Description]:

B-Raf IN 2 is a potent and selective BRAF inhibitor extracted from patent WO2021116055A1, compound Ia. B-Raf IN 2 can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> MAPK/ERK Pathway >> Raf

[Target]

BRafV600E


[In Vitro]

B-Raf IN 2 shows considerably less paradoxial activation of the MAPK signaling pathway while retaining high potency[1].

[References]

[1]. Dolente C, et, al. New methylquinazolinone derivatives. WO2021116055A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H17F2N5O4S

[ Molecular Weight ]:
461.44


Related Compounds