HIV-1 inhibitor-19

Names

[ CAS No. ]:
2649837-82-9

[ Name ]:
HIV-1 inhibitor-19

Biological Activity

[Description]:

HIV-1 inhibitor-19 is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-19 maintains its inhibitory activity against L100I, K103N and V106A/ F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection

[References]

[1]. Shujing Xu, et al. Indolylarylsulfones bearing phenylboronic acid and phenylboronate ester functionalities as potent HIV‑1 non-nucleoside reverse transcriptase inhibitors. Bioorg Med Chem. 2022 Jan 1;53:116531.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H22BClN2O5S

[ Molecular Weight ]:
496.77

Related Compounds