BCR-ABL-IN-4

Names

[ CAS No. ]:
2669790-59-2

[ Name ]:
BCR-ABL-IN-4

Biological Activity

[Description]:

BCR-ABL-IN-4 is a BCR-ABL inhibitor with anticancer effects. BCR-ABL-IN-4 inhibits the cancer cell growth with IC50 values of 0.67 nM and 16 nM for K562 cells and BCR-ABL T315I transfected Ba/F3 cells, respectively (WO2021143927A1; compound 11)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl

[References]

[1]. Yinsheng Zhang, et al. Compound acting as bcr-abl inhibitor. WO2021143927A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H24ClF2N5O4

[ Molecular Weight ]:
555.96

Related Compounds