JAK3/BTK-IN-5

Names

[ CAS No. ]:
2673196-75-1

[ Name ]:
JAK3/BTK-IN-5

Biological Activity

[Description]:

JAK3/BTK-IN-5 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets for autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway exhibits synergistic effects. JAK3/BTK-IN-5 has the potential for the research of JAK3 kinase and/or BTK-related diseases (extracted from patent WO2021147953A1, compound 35)[1]

[Related Catalog]:

Signaling Pathways >> JAK/STAT Signaling >> JAK
Signaling Pathways >> Epigenetics >> JAK
Signaling Pathways >> Stem Cell/Wnt >> JAK
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

[References]

[1]. Baoguo Zhang, et al. Pyrimidinopyrimidine and pentacyclic derivatives and their applications. Patent WO2021147953A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H22ClN7O2

[ Molecular Weight ]:
415.88

Related Compounds