5-Pyrimidinemethanol, a-(2,4-dichlorophenyl)-a-phenyl-

Names

[ Name ]:
5-Pyrimidinemethanol, a-(2,4-dichlorophenyl)-a-phenyl-

[Synonym ]:
rac-(R)-(2,4-dichlorophenyl)phenyl(pyrimidin-5-yl)methanol
EL-273
(RS)-2,4-dichloro-α-(pyrimidin-5-yl)benzhydryl alcohol
α-(2,4-dichlorophenyl)-α-phenyl-5-pyrimidinemethanol
(2,4-dichlorophenyl)-phenyl-pyrimidin-5-ylmethanol
Caswell No. 861A
TRIARIMOL

Chemical & Physical Properties

[ Density]:
1.376g/cm3

[ Boiling Point ]:
501.6ºC at 760mmHg

[ Molecular Formula ]:
C₁₇H₁₂Cl₂N₂O

[ Molecular Weight ]:
331.19600

[ Flash Point ]:
257.2ºC

[ Exact Mass ]:
330.03300

[ PSA ]:
46.01000

[ LogP ]:
4.06760

[ Vapour Pressure ]:
6.99E-11mmHg at 25°C

[ Index of Refraction ]:
1.643

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV9282000

CHEMICAL NAME :: 5-Pyrimidinemethanol, alpha-(2,4-dichlorophenyl)-alpha-phenyl-

CAS REGISTRY NUMBER :: 26766-27-8

BEILSTEIN REFERENCE NO. :: 0756381

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C17-H12-Cl2-N2-O

MOLECULAR WEIGHT :: 331.21

WISWESSER LINE NOTATION :: T6N CNJ EXQR&R BG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 525 mg/kg/14D-C

TOXIC EFFECTS :: Liver - other changes Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 50 ppm

REFERENCE :: RSTUDV Rivista di Scienza e Technologia degli Alimenti e di Nutrizione Umana. Review of Science and Technology of Food and Human Nutrition. (Bologna, Italy) V.5-6, 1975-76. Discontinued. Volume(issue)/page/year: 6,161,1976

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22

[ HS Code ]:
2933599090

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%