Tyk2-IN-9

Names

[ CAS No. ]:
2694816-85-6

[ Name ]:
Tyk2-IN-9

Biological Activity

[Description]:

Tyk2-IN-9 (Compound 26) is a selective Tyk-2 inhibitor with IC50s of 0.076 and 1.8 nM for TYK2-JH2 and JAK1-JH2, respectively. Tyk2-IN-9 can be used for the research of inflammatory or autoimmune disease[1].

[Related Catalog]:

Signaling Pathways >> JAK/STAT Signaling >> JAK
Signaling Pathways >> Epigenetics >> JAK
Signaling Pathways >> Stem Cell/Wnt >> JAK
Research Areas >> Inflammation/Immunology

[References]

[1]. Qiuwen WANG, et al. Tyk-2 inhibitor. WO2021170046A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H25N9O3

[ Molecular Weight ]:
451.48

Related Compounds