CARBENICILLIN PHENYL SODIUM
Names
[ CAS No. ]:
27025-49-6
[ Name ]:
CARBENICILLIN PHENYL SODIUM
[Synonym ]:
Carfecilina [INN-Spanish]
Carfecilline
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(3-oxo-3-phenoxy-2-phenylpropanoyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Carbenicillin phenyl
Carfecilline [INN-French]
Carfecillinum
Carfecillinum [INN-Latin]
Carbenicillin phenyl ester
Carfecilina
Chemical & Physical Properties
[ Density]:
1.44g/cm3
[ Boiling Point ]:
770.9ºC at 760mmHg
[ Molecular Formula ]:
C23H22N2O6S
[ Molecular Weight ]:
454.49600
[ Flash Point ]:
420ºC
[ Exact Mass ]:
454.12000
[ PSA ]:
141.80000
[ LogP ]:
2.78570
[ Vapour Pressure ]:
5.33E-25mmHg at 25°C
[ Index of Refraction ]:
1.672
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ON9109000
- CHEMICAL NAME :
- Malonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3 .2.0)hept-6-yl)-2- phenyl-, 1-phenyl ester
- CAS REGISTRY NUMBER :
- 27025-49-6
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C23-H22-N2-O6-S
- MOLECULAR WEIGHT :
- 454.53
- WISWESSER LINE NOTATION :
- T45 ANV ESTJ CMVYR&VOR& F1 F1 GVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 980 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 25,513,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3924 mg/kg
- TOXIC EFFECTS :
- Blood - agranulocytosis Blood - thrombocytopenia
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 25,513,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 728 mg/kg
- TOXIC EFFECTS :
- Blood - agranulocytosis Blood - thrombocytopenia
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 25,513,1980