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RET-IN-5

Names

[ CAS No. ]:
2725770-20-5

[ Name ]:
RET-IN-5

Biological Activity

[Description]:

RET-IN-5 is a potent RET (rearranged during transfection) inhibitor with an IC50s of 0.4 nM and 135.1 nM for RET and VEGFR2, respectively (WO2021213476A1, compound 18)[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Pyrazolo[1,5-a]pyridine derivative, preparation method therefor, and composition and use thereof. WO2021213476A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H26FN9O

[ Molecular Weight ]:
535.57


Related Compounds