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SOS1-IN-4

Names

[ CAS No. ]:
2738392-83-9

[ Name ]:
SOS1-IN-4

Biological Activity

[Description]:

SOS1-IN-4 is a potent SOS1 inhibitor with an IC50 of 56 nM for KRAS-C12C/SOS1 interaction (WO2021228028 A1, example 65)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRAS-C12C/SOS1:56 nM (IC50)


[References]

[1]. Sos1 inhibitor containing phosphorus. WO2021228028A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H29F2N4O2P

[ Molecular Weight ]:
474.48

Related Compounds