Dimethylamino-PEG3

Names

[ Name ]:
Dimethylamino-PEG3

[Synonym ]:
Kaolizer 23NP
23P
Dimethylaminoethoxyethoxy-ethanol
Ethanol,2-[2-[2-(dimethylamino)ethoxy]ethoxy]
Kaolizer 23
Dimethylaminotriaethylenalkohol
Kaolizer 23P
2-[2-(2-dimethylamino-ethoxy)-ethoxy]-ethanol
1-O<2'-Dimethylaminoethoxyethyl>ethylenglykol
2-{2-[2-(dimethylamino)ethoxy]ethoxy}ethan-1-ol
2-[2-(2-Dimethylamino-aethoxy)-aethoxy]-aethanol

Biological Activity

[Description]:

Dimethylamino-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Molecular Formula ]:
C₈H₁₉NO₃

[ Molecular Weight ]:
177.24100

[ Exact Mass ]:
177.13600

[ PSA ]:
41.93000

Safety Information

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%