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8-Isoprostaglandin F2α

Names

[ CAS No. ]:
27415-26-5

[ Name ]:
8-Isoprostaglandin F2α

[Synonym ]:
Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,8β,9α,11α,13E,15S)-
(Z)-7-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid
(5Z,8β,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid
8-epi-Prostaglandin F2α
8-epi-prostaglandin F2alpha

Biological Activity

[Description]:

8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.

[Target]

Human Endogenous Metabolite

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
531.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H34O5

[ Molecular Weight ]:
354.481

[ Flash Point ]:
289.0±26.6 °C

[ Exact Mass ]:
354.240631

[ PSA ]:
97.99000

[ LogP ]:
2.14

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.569

Related Compounds