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KRAS G12D inhibitor 3 TFA

Names

[ CAS No. ]:
2757095-12-6

[ Name ]:
KRAS G12D inhibitor 3 TFA

Biological Activity

[Description]:

KRAS G12D inhibitor 3 TFA is a KRAS G12D inhibitor with an IC50 of <500 nM. KRAS G12D inhibitor 3 TFA has antitumor effects (WO2022002102A1; compound 146)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRas G12D:<500 nM (IC50)


[References]

[1]. Xing DAI, et al. Quinazoline compounds, preparation methods and uses thereof. WO2022002102A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C36H32ClF6N5O4

[ Molecular Weight ]:
748.11

Related Compounds