3CPLro-IN-2

Names

[ Name ]:
3CPLro-IN-2

Biological Activity

[Description]:

3CPLro-IN-2 (compound C1) is a potent and orally active inhibitor of SARS-CoV-2 3CLpro with an IC50 and Ki of 1.55 and 6.09 μM, respectively. 3-Chymotrypsin-like cysteine protease (3CLpro) is an indispensable protein in viral replication and represents an attractive drug target for fighting COVID-19[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Zhang JW, et al. Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19. Eur J Med Chem. 2022;228:114030.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₂₄BrNO₂

[ Molecular Weight ]:
534.44

3CPLro-IN-2

Names

Biological Activity

Chemical & Physical Properties

Related Compounds