3-(Allyloxy)-1,2-benzothiazole 1,1-dioxide
Names
[ CAS No. ]:
27605-76-1
[ Name ]:
3-(Allyloxy)-1,2-benzothiazole 1,1-dioxide
[Synonym ]:
3-allyloxy-1,2-benzisothiazole-1,1-dioxide
3-(2-Propenyloxy)-1,2-benzisothiazole 1,1-dioxide,3-Allyloxy-1,2-benzisothiazole 1,1-dioxide
Probenazole Standard
3-(Prop-2-en-1-yloxy)-1,2-benzisothiazole 1,1-dioxide
3-(prop-2-en-1-yloxy)-1λ6,2-benzothiazole-1,1-dione
ORYZEMATE
oryzaemate
MFCD00274602
1,2-Benzisothiazole, 3-(2-propen-1-yloxy)-, 1,1-dioxide
po-20
1,2-Benzisothiazole, 3-(2-propenyloxy)-, 1,1-dioxide (9CI)
3-(Allyloxy)-1,2-benzothiazole 1,1-dioxide
3-Allyloxy-1,2-benz[d]isothiazole 1,1-dioxide
3-(allyloxy)-1,2-benzisothiazole 1,1-dioxide
3-allyloxy-1,2-benzothiazole 1,1-dioxide
ORYZAMATE
Probenazole
3-(Allyloxy)benzo[d]isothiazole 1,1-dioxide
3-(2-Propèn-1-yloxy)-1,2-benzothiazole-1,1-dioxyde
PROBENAZOIE
3-(2-propen-1-yloxy)-1,2-benzisothiazole 1,1-dioxide
3-(Prop-2-en-1-yloxy)-1,2-benzisothiazol-1,1-dioxid
3-(prop-2-en-1-yloxy)-1,2-benzothiazole 1,1-dioxide
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
369.0±35.0 °C at 760 mmHg
[ Melting Point ]:
139 °C
[ Molecular Formula ]:
C10H9NO3S
[ Molecular Weight ]:
223.248
[ Flash Point ]:
177.0±25.9 °C
[ Exact Mass ]:
223.030319
[ PSA ]:
64.11000
[ LogP ]:
1.87
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.604
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DE4155000
- CHEMICAL NAME :
- 1,2-Benzisothiazole, 3-(allyloxy)-, 1,1-dioxide
- CAS REGISTRY NUMBER :
- 27605-76-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C10-H9-N-O3-S
- MOLECULAR WEIGHT :
- 223.26
- WISWESSER LINE NOTATION :
- T56 BSWNJ DO2U1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2030 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 7,307,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 850 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 13,219,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (37),37,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2750 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 13,205,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 745 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 13,205,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (37),37,1980
Safety Information
[ Hazard Codes ]:
Xn,Xi
[ Risk Phrases ]:
R22:Harmful if swallowed. R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .
[ Safety Phrases ]:
S36/37
[ RIDADR ]:
3276
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2934200013
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934200013
[ Summary ]:
2934200013 3-(allyloxy)benzo[d]isothiazole 1,1-dioxide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%
Articles
Biosci. Biotechnol. Biochem. 65(1) , 205-8, (2001)
Probenazole (PBZ) induces non-race specific resistance in rice plants against rice blast fungus and PBZ1 was identified as a PBZ-inducible gene from rice. The induction of PBZ1 expression in suspensio...
Different responses of two genes associated with disease resistance loci in maize (Zea mays L.) to 3-allyloxy-1,2-benzothiazole 1,1-dioxide.Curr. Issues Mol. Biol. 11 Suppl 1 , i85-94, (2009)
Probenazole (3-allyloxy-1,2-benzothiazole 1,1-dioxide, PBZ) is a bactericide and fungicide that acts by inducing plant defense systems. It has been shown to induce the expression of NBS-LRR genes like...
Proteome analysis of probenazole-effect in rice-bacterial blight interactions.Protein Pept. Lett. 16(9) , 1041-52, (2009)
To study the effect of probenazole on the induced systemic resistance mechanism of rice-bacterial interaction, a proteomic approach was applied. Oryza sativa cv. Java 14 seedlings were treated with pr...