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USP7-IN-11

Names

[ CAS No. ]:
2763872-32-6

[ Name ]:
USP7-IN-11

Biological Activity

[Description]:

USP7-IN-11 is a potent ubiquitin-specific protease 7 (USP7) (Deubiquitinase) inhibitor with an IC50 of 0.37 nM. USP7-IN-11 has anticancer effects (WO2022048498A1; Example 187)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase

[In Vitro]

USP7-IN-11（实施例 187 ; for 72hours）抑制 RS4;11 细胞的增殖，IC50 为 1.23 nM[1]。

[References]

[1]. Deng Hou, et al. Usp7 inhibitor. WO2022048498A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H27ClN6O2S

[ Molecular Weight ]:
559.08

Related Compounds